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Molecular farming / pharming / biopharming - patents for metabolic intervention - Biodegradable Plastics

Issued patents are differentiated from applications in that applications are italicized.

Aquin, S., Snell, K. D., Peoples, O. P., WO 0240690, pub May 23, 2002, Production of medium chain length polyhydroxyalkanoates from fatty acid biosynthetic pathways, Metabolix, (plastics)


Aquin, S., Vezina, L-P., US 6,492,134, Dec 10, 2002, Method for producing polyhydroxyalkanoates in recombinant organisms, U. Laval/ AAFC

Asrar, J., Mitsky, T. A., Shah, D. T., US 6,091,002, July 18, 2000, Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants, Monsanto, (plastics)

Asrar, J., Mitsky, T. A., Shah, D. T., US 6,228,623, May 8, 2000, Polyhydroxyalkanoates of narrow molecular weight distribution prepared in transgenic plants, Monsanto, (plastics)

Betlach, M. C., Kealey, J. T., Gutterson, N., Ralston, E., US 6,262,340, Jul 17, 2001, Production of polyketides in plants, Kosan Biosciences Inc, (plastics)

Boynton, L., Patterson, N., Huisman, G. W., Moloney, M., Snell, K., Peoples, O. P., WO 9945122, pub Sept 10, 1999, Modification of fatty acid metabolism in plants, Metabolix, (plastics)

Bright, S. W. J., Byrom, D., Fentem, P. A., US 5,502,273, Mar 26, 1996, Production of polyhydroxy alkanoate in plants, Zeneca, (plastic), also EP589898A1, and WO9219747A1.

Gruys, K. J., Mitsky, T. A., Slater, S. C., Padgette, S. R. Stark, D. M., US 5,942,660, Aug 24, 1999, Methods of optimizing substrate pools and biosynthesis of poly-B-hydroxybutyrate-co-poly-B-hydroxyvalerate in bacteria and plants, Monsanto Company, (plastic). Also WO9800557A2

Gruys, K. J., Mitsky, T. A., Slater, S. C., Padgette, S. R. Stark, D. M., US 5,958,745, Sept 28, 1999, Methods of optimizing substrate pools and biosynthesis of poly-B-hydroxybutyrate-co-poly-B-hydroxyvalerate in bacteria and plants, Monsanto Company, (plastic). Also WO9800557A2

Horowitz, D., WO 0068409, pub Nov 16, 2000, Methods for purifying polyhydroxyalkanoates, Metabolix, (Plastics)

Huisman, G. W., Madison, L., Peoples, O. P., WO 0043523, pub July 27, 2000, Transgenic systems for the manufacture of poly(3-hydroxy-butyrate-co-3-hydroxyhexanoate, Metabolix, (plastics)

Huisman, G. W. , Skraly, F., Martin, D. P., Peoples, O. P., US 6,316,262, Nov 13, 2001, Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids, Metabolix Inc, (plastics), also WO 9914313

Kruger, N., Steinbuchel, A., US 5,750,848, May 12, 1998, DNA sequence useful for the production of polyhydroxyalkanoates, Monsanto, (plastics)

Kruger, N., Steinbuchel, A., US RE37,543, Feb 5, 2002, DNA sequence useful for the production of polyhydroxyalkanoates, Monsanto, (plastics)

Liebergesell, M., Fallis, P. L., Dong, J. G., Li, C. P., Nichols, S. E., US 6,475,734, Nov 5, 2002, Polyhydroxyalkanoate synthase genes, Pioneer Hi-bred Intl.

Martin, D. P., Peoples, O. P., Williams, S. F., US 6,083,729, July 4, 2000, Methods for isolating polyhydroxyalkanoates from plants, Metabolix,Inc., also AU751673

Merrill, E. W., Sagar, A., US 5,459,258, Oct 17, 1995, Polysaccharide based biodegradable thermoplastic materials, MIT, (plastic)

Nichols, S. E., US 6,087,559, July 11, 2000, Plant cells and plants transformed with Streptococcus mutans gene encoding glucosyltransferase B enzymes, Pioneer Hi-breds Intl., (glucans/plastic). AU 709402B2

Nichols, S. E., US 6,127,602, Oct 3, 2000, Plant cells and plants transformed with Streptococcus mutans gene encoding glucosyltransferase D enzymes, Pioneer Hi-breds Intl., (glucans/plastic).

Nichols, S. E., US 6,127,603, Oct 3, 2000, Plant cells and plants transformed with Streptococcus mutans gene encoding glucosyltransferase C enzyme, Pioneer Hi-breds Intl., (glucans/plastic).

Peoples, O. P., Boynton, L., Huisman, G. W., Moloney, M., Patterson, N., Snell, K., WO 9945122, pub sept 10, 1999, Modification of fatty acid metabolism in plants, Metabolix, (plastics)


Peoples, O. P., Gerngross, T. U., Sinskey, A. J., US 5,480,794, Jan 2, 1996, Overproduction and purification of soluable PHA synthase, MIT, (plastic)

Peoples, O. P., Moloney, M., Patterson, N., Snell, K. D., US 6,586,658, July 1, 2003, Modification of fatty acid metabolism in plants, Metabolix

Peoples, O.P., Sinskey, A. J., US 5,229,279, July 20, 1993, Method for producing novel polyester biopolymers, MIT, (plastic).

Peoples, O.P., Sinskey, A. J., US 5,245,023, Sept 14, 1993, Method for producing novel polyester biopolymers, MIT, (plastic).

Peoples, O. P., Sinskey, A. L., US 5,250,430, Oct 5, 1993, Polyhydroxyalkanoate polymerase, MIT, (plastic).

Peoples, O. P., Sinskey, A. J., US 5,512,669, April 30, 1996, Gene encoding bacterial acetoacetyl-CoA reductase, MIT, (plastic)

Peoples, O. P., Sinskey, A. J., US 5,534,432, July 9, 1996, Polyhydroxybutyrate polymerase, MIT, (biodegradable plastics).

Peoples, O. P., Sinskey, A. J., US 5,661,026, Aug 26, 1997, Gene encoding bacterial beta-ketothiolase, MIT, (plastic).

Peoples, O. P., Sinskey, A. J., US 5,663,063, Sept 2, 1997, Method for producing polyester biopolymers, MIT, (plastic).

Peoples, O. P., Sinskey, A. J., US 5,798,235, Aug 25, 1998, Gene encoding bacterial acetoacetyl-CoA reductase, MIT, (plastic)

Peoples, O. P., Sinskey, A. J., EP482077B1, Oct 21, 1998, Method for producing polyester biopolymers, MIT, (plastic)

Skraly, F. A., Peoples, O.P., US 6,323,010, Nov 27, 2001, Polyhydroxyalkanoate biopolymer compositions, Metabolix Inc, (plastics)

Skraly, F. A., Peoples, O. P., US 6,329,183, Dec 11, 2001, Polyhydroxyalkanoate production from polyols, Metabolix

Somerville, C. R., Nawrath, C., Poirier, Y.,US 5,610,041, Mar 11, 1997, Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants, Michigan State Univ, (plastics) also WO9505472A2

Somerville, C. R., Poirier, Y., Dennis, D. E., US 5,650,555, July 22, 1997, Transgenic plants producing polyhydroxyalkanoates, Michigan State Univ., (plastics), also WO9302187A1,and CA 2113412AA.

Srienc, F., Somers, D. A., Hahn, J. J., Eschenlauer, A. C., US 6,103,956, Aug 15, 2000, Polyhydroxyalkanoate synthesis in plants, Univ of Minnesota

Yamaguchi, I., Nakashita, H., Yoshioka, K., Doi, Y., US 6,620,601, Sept 16, 2003, Methods for transformation of plants, transformed plants and processes for preparation of polyesters, Riken, (chloroplasts)

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