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Molecular farming / pharming / biopharming patents for vaccine production in plants.

Issued patents are differentiated from applications in that applications are italicized.

Arakawa, T., Langridge, W. H. R., Yu, J., WO 0155169, pub Aug 2, 2001, Transgenic plant-based vaccines, Loma Linda Univ, (cholera vaccine)

Arntzen, C. J., Mason, H. S., Haq, T. A., US 6,194,560, Feb 27, 2001, Oral immunization with transgenic plants, Texas A & M Univ.,

Brandle, J., Babiuk, L., Rymerson, R., WO 0194392, pub Dec 13, 2001, Recombinant subunit proteins from porcine parovirus produced in plants, VIDO

Brandle, J., Erickson, L., Rymerson, R., Yoo, D., Zhang, J., CA 2319141, filed Jan 27, 1999, Porcine reproductive and respiratory syndrome oral vaccine production in plants, AAFC, (vaccine)

Brandle, J., Rymerson, R., Zhang, J., Yoo, D., Erickson, L., CA 2221843, filed Jan 27, 1998, Porcine reproductive and respiratory syndrome oral vaccine production in plants, AAFC, (vaccine)

Curtiss, R., III., Cardineau, G. A., US 5,654,184, Aug 5, 1997, Oral immunization by transgenic plants, Washington Univ, (Mycogen), (vaccines).

Curtiss, R., III., Cardineau, G. A., US 5,679,880, Oct 21, 1997, Oral immunization by transgenic plants, Washington Univ, (Mycogen), (vaccines).

Curtiss, R., III., Cardineau, G. A., US 5,686,079, Nov 11, 1997, Oral immunization by transgenic plants, Washington Univ, (Mycogen), (vaccines).

Griot-Wenk, M. E., Goff, S. A., Heifertz, P. B., Tuttle, A. B., WO0020612, pub April 13, 2000, Therapeutically active proteins in plants, Novartis, (vaccines)

Howard, J. A., All, B. P., US2002058312, pub May 16, 2002, Expression cassettes and methods for delivery of animal vaccines, Prodigene Inc

Koprowski, H., Yusibov, V., Hooper, D. C., Modelska, A., US 6,042,832, Mar 28, 2000, Polypeptides fused with alfalfa mosiac virus or ilarvirus capsid, Thomas Jefferson Univ, (vaccine)

Koprowski, H., Yusibov, V., Hooper, D. C., Modelska, A., US 6,448,070, Sept 10, 2002, Polypeptides fused with alfalfa mosiac virus or ilarvirus capsid, Thomas Jefferson Univ, (vaccine)

Lam, D. M., Arntzen, C. J., US 5,484,719, Jan 16, 1996, Vaccines produced and administered through edible plants, Edible Vaccines Inc ( Prodigene).

Lam, D, M-K., Arntzen, C. J., US 5,612,487, Mar 18, 1997, Anti-viral vaccines expressed in plants, Edible Vaccines Inc (Prodigene).

Lam, D, M-K., Arntzen, C. J., Mason, H. S., US 6,034,298, Mar 7, 2000, Vaccines expressed in plants, Prodigene Inc. also WO9420135A1,and EP728014A1.

Langridge, W. H. R., Arakawa, T., Chong, D., Merritt, J. L., WO9918225A1, pub Apr 15, 1999, Expression of cholera toxin B subunit in transgenic plants and efficacy thereof in oral vaccines, Loma Linda Univ.

Mason, H. S., Thanavala, Y., Arntzen, C. J., Richter, E., US 6,551,820, April 22, 2003, Expression of immunogenic hepatitis B surface antigens in transgenic plants, Boyce Thompson Inst. (Hepatitis vaccine)

Merot, B., Baudino, S., Gruber, V., Bournat, P., Lenee, P., Riviere, M. E., Audonnet, J-C., WO 9743428, pub Nov 20, 1997, Transgenic plants expressing rabies glycoprotein G, and glycoproteins thus obtained, Biocem, (rabies vaccine), also CA2254115

Moloney, M. M., Schryvers, A. B., Alcantara, J., Hutchins, W. A., WO 0195934, pub Dec 20, 2001, The use of plant oil-bodies in vaccine delivery systems, SemBioSys Genetics Inc.

Reinl, S. J., Turpen, T. H., WO 0168682, pub Sept 20, 2001, Self antigen vaccines for treating B cell lymphomas and other cancers, Large Scale Biology

Rymerson, R., Zhang, J., Yoo, Erickson, L., Brandle, J., WO 9937784A1, pub July 29, 1999, Porcine reproductive and respiratory syndrome oral vaccine production in plants, Univ of Guelph.

Stewart, C. N., Jr., McKee, M. L., O'Brien, A. D., Wachtel, M. R., US 6,261,561, July 17, 2001, Method of stimulating an immune response by administration of host organisms that express intimin alone or as a fusion protein with one or more other antigens, Henry M. Jackson Foundation, (edible vaccine against E. coli 0157 - animals and humans)

Stewart, C. N., Jr., McKee, M. L., O=Brien, A. D., Wachtel, M. R., US 6,406,885, June 18, 2002, Plants and plant cells expressing histidine tagged intimin, Henry M. Jackson Foundation, (vaccine against E. coli 0157)

Stram, Y., Rogel, A., Sela, I., Edelbaum, O., Shachar, Y., Zanberg, Y., Gontmakher, T., Khayat, E., US 6,528,063, Mar 4, 2003, Recombinant vaccines against IBDV, Meristem, (poultry vaccine)

Tackaberry, E., Dudani, A., Ganz, P. Altosaar, I. and Sardana, R. Production of therapeutic proteins in transgenic cereal crops. US 20030159182. Filing Date Aug. 29, 2002. Also filed in Canada CA 2,400,887; CA 2,356,473. ( vaccine against herpes viruses)

Wang, X., Fang, R., Zhang, G., CN1286120, pub Mar 7, 2001, Cholera vaccine prepared from transgenic carrot and its preparing process, Chinese Inst of Microbiology, (cholera vaccine)


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